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Study identifier: NCT06500208 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant Adebrelimab and Chemotherapy in High-rish ER+/HER2- BC

Condition: Breast Cancer  ·  Sponsor: Shanghai Jiao Tong University School of Medicine

PhasePhase 2
Planned participants48
Who can joinFemale, 18 Years to 65 Years
Healthy volunteersNo

About this study

Investigators plan to conduct a single-arm clinical study of adebelimab, a novel PD-L1 inhibitor, in the neoadjuvant treatment of early or locally advanced high-risk ER+/HER2- breast cancer, to explore whether the addition of immune checkpoint inhibitors to traditional neoadjuvant chemotherapy can improve the pathologic complete response rate (pCR) of patients, evaluate its therapeutic safety, and further analyze the biomarkers of the efficacy of neoadjuvant immunotherapy for ER+/HER2- breast cancer, so as to support the clinical application of the drug.

This description comes directly from the study's public registry record.

Talk to the study team

Haoyu Wang  ·  86 021-64370045  ·  meredithwhy@163.com

Xiaosong Chen  ·  86 021-64370045  ·  chenxiaosong0156@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ruijin HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06500208