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Study identifier: NCT06498947 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Factors Influencing Physiological Hyperopia in Children

Condition: Myopia Progression  ·  Sponsor: Beijing Tongren Hospital

PhaseN/A
Planned participants1006
Who can joinAll sexes, 6 Years to 9 Years
Healthy volunteersYes

About this study

The trend of myopia in children and its low age is a major social and public health problem in China. More seriously, retinopathy associated with high myopia has become the number one cause of irreversible blinding eye disease in adults in some parts of China. Physiological hyperopia has a protective effect on preventing the onset of myopia, and is one of the strongest predictors of myopia on its own, which is significant in curbing myopia from occurring at a younger age and preventing the development of high myopia before adulthood. However, it is not yet known how the physiological hyperopia changes in childhood, the stage at which the critical inflection point occurs, which key factors lead to the rapid fading of the physiological hyperopia and progression to myopia, and the strength of its effect. In the early stage of the study, the research group established a prospective cohort of preschoolers based on natural population sampling, which included a total of 2109 preschoolers aged 3-6 years from 22 kindergartens in a district in Beijing, and completed a 2-year follow-up, obtaining exploratory results on the changing pattern of physiological hyperopia and key influencing factors in younger children. The group will add new samples to the existing whole cohort sampling cohort and adopt the design scheme of prospective nested case-control study to determine the changing trend of fading trajectory of physiological hyperopia in school-age children, key inflection points and ke…

This description comes directly from the study's public registry record.

Talk to the study team

Huaying Xu, MD  ·  18813072901  ·  xuhuaying99@163.com

YH Jiao, Ph D.  ·  13051612248  ·  yhjiao2001@aliyun.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Tongren HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06498947