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Study identifier: NCT06498037 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Optimizing Subcutaneous FEntanyl titRation: RApid Achievement of Adequate Exposure When Treating Cancer-Related paIn.

Condition: Cancer Pain  ·  Sponsor: Erasmus Medical Center

PhasePhase 4
Planned participants45
Who can joinAll sexes, 18 Years to 120 Years
Healthy volunteersNo

About this study

The primary objective is to evaluate the effect of loading boluses when dose incresaing treatment with SC fentanyl in patients with cancer. The primary endpoint of this study is to prove the non-inferiority of fentanyl plasma concentrations 12 hours after dose augmentation compared to 48 hours after dose augmentation within each patient. Patients will be treated with additional loading boluses and plasma-PK samples will be obtained.

This description comes directly from the study's public registry record.

Talk to the study team

Bram C Agema  ·  +31107040704  ·  b.agema@erasmusmc.nl

Always discuss trial participation with your own doctor first.

Locations (1)

Erasmus Medical CenterRotterdam, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06498037