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Study identifier: NCT06497894 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

No More Sleepless Nights in Perimenopause

Condition: Insomnia · Menopause  ·  Sponsor: Insel Gruppe AG, University Hospital Bern

PhasePhase 4
Planned participants54
Who can joinFemale, 45 Years to 69 Years
Healthy volunteersYes

About this study

The goal of the clinical trial is to learn if Hormone Replacement Therapy (HRT) and Cognitive Behavioral Therapy (CBT-I) can treat insomnia in menopausal women. The main questions it aims to answer are: * Are HRT and CBT-I effective in reducing insomnia in menopausal women? * Are HRT and CBT-I comparable in terms of reducing insomnia severity in this population? Researchers will compare HRT and CBT-I to an active control group, receiving sleep hygiene instructions. Participants will: * Complete a screening and baseline assessment * Receive Hormone Replacement Therapy (as prescribed), Cognitive Behavioral Therapy (1/week), or sleep hygiene instructions (1/week) for 8 weeks. * Keep a daily diary (sleep e-diary), to assess sleep-quality. * Wear an electroencephalogram (EEG) during 6 nights (3 at baseline \& 3 post-intervention), to assess deep sleep cycles and waking episodes. * Receive a phone call for intervention compliance * Complete a post-intervention assessment.

This description comes directly from the study's public registry record.

Talk to the study team

Petra Stute, Prof.  ·  +41 31 632 1010  ·  petra.stute@insel.ch

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital of Bern, Department of Gynecological Endocrinology & Reproductive MedicineBern, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT06497894