Condition: Mevalonate Kinase Deficiency · Sponsor: University Hospital, Motol
Mevalonate kinase deficiency (HyperIgD syndrome, HIDS) is an inborn error of immunity caused by a block in the mevalonate pathway. The subsequent lack of isoprenoids with antiinflammatory properties might contribute to the autoinflammatory nature of the disease. A pilot study aims to verify the safety and efficacy of the dietary supplement Geranylgeraniol, aiming at a mitigation of isoprenoids deficiency caused by the above-mentioned block in the MVK pathway.
This description comes directly from the study's public registry record.
Anna Šedivá, Prof · +420603166112 · anna.sediva@fnmotol.cz
Eva Aljamal, Mgr · +420601354311 · eva.aljamal@fnmotol.cz
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| University Hospital, Motol | Prague, Czechia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06497829