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Study identifier: NCT06496971 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

Condition: Glioblastoma Multiforme · Glioblastoma · Glioblastoma Multiforme, Adult  ·  Sponsor: NaviFUS Corporation

PhasePhase 3
Planned participants32
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This will be a prospective, randomized, standard of care (SoC) controlled, parallel, open-label, multicenter pivotal study to investigate the efficacy and safety of Bevacizumab (BEV) in combination with or without microbubble (MB)-mediated FUS in patients with recurrent GBM. BEV represents the physician's best choice for the standard of care in rGBM after previous treatment with surgery (if appropriate), standard radiotherapy with temozolomide chemotherapy, and with adjuvant temozolomide.

This description comes directly from the study's public registry record.

Talk to the study team

Sheang-Tze Fung, Ph.D.  ·  02-25860560  ·  stfung@navifus.com

Arthur Lung, Ph.D.  ·  arthur.lung@navifus.com

Always discuss trial participation with your own doctor first.

Locations (2)

National Taiwan University HospitalTaipei, TaiwanRecruiting
Linkou Chang Gung Memorial HospitalTaoyuan, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT06496971