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Study identifier: NCT06496750 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Ketamine for Methamphetamine Use Disorder

Condition: Substance Use Disorders · Substance Use · Methamphetamine Abuse  ·  Sponsor: University of Texas Southwestern Medical Center

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study aims to determine whether treatment response with IV ketamine is superior to treatment response with IV midazolam in adults with moderate to severe MUD. The study design is a 12-week randomized, double-blind, controlled trial comparing intravenous (IV) ketamine against IV midazolam, delivered over six weeks in 120 adults with moderate to severe methamphetamine use disorder (MUD).

This description comes directly from the study's public registry record.

Talk to the study team

Angela Casey-Willingham  ·  214-648-4689  ·  Angela.Casey-Willingham@UTSouthwestern.edu

Always discuss trial participation with your own doctor first.

Locations (5)

Alameda Health SystemSan Leandro, California, United StatesRecruiting
Interdisciplinary Substance Use and Brain Injury FacilityAlbuquerque, New Mexico, United StatesCompleted
Addiction Institute of Mount SinaiNew York, New York, United StatesTerminated
Prisma HealthGreenville, South Carolina, United StatesRecruiting
UT Southwestern Medical CenterDallas, Texas, United StatesActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT06496750