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Study identifier: NCT06496581 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)

Condition: Prostate Cancer Metastatic  ·  Sponsor: UNICANCER

PhasePhase 3
Planned participants500
Who can joinMale, 18 Years to 80 Years
Healthy volunteersNo

About this study

PEACE-6 Poor Responders is an international, multicenter, open-label, controlled, randomized, phase III trial to evaluate the efficacy and safety of 177Lu-PSMA-617 when administered on top of the ongoing standard systemic treatment compared to standard systemic treatment alone in patients with de novo metastatic hormone-sensitive prostate cancer (mHSPC) who do not present with a satisfactory response characterized by a serum prostatic specific antigen (PSA) level of ≥ 0.2 ng/mL at 6 to 8 months after systemic treatment initiation for mHSPC (i.e. poor responders) in the absence of evidence of cancer progression (including a rising PSA level).

This description comes directly from the study's public registry record.

Talk to the study team

Florence TANTOT  ·  +33 (1) 73.77.55.43  ·  f-tantot@unicancer.fr

Catherine LEGER  ·  +33 (7) 79.83.23.98  ·  c-leger@unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (25)

Institut de Cancérologie de l'OuestAngers, FranceNot Yet Recruiting
Institut BergoniéBordeaux, FranceNot Yet Recruiting
CHRU BrestBrest, FranceNot Yet Recruiting
Centre Francois BaclesseCaen, FranceNot Yet Recruiting
CHU Henri MondorCréteil, FranceNot Yet Recruiting
Centre Georges-François LeclercDijon, FranceNot Yet Recruiting
CHU GrenobleGrenoble, FranceNot Yet Recruiting
Centre Léon BerardLyon, FranceNot Yet Recruiting
Institut Paoli-CalmettesMarseille, FranceRecruiting
CHRU NancyNancy, FranceNot Yet Recruiting
Centre Antoine LacassagneNice, FranceNot Yet Recruiting
Hôpital CochinParis, FranceNot Yet Recruiting

+ 13 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06496581