Condition: Hypertension · Vascular Stiffness · Aging · Sponsor: VA Office of Research and Development
Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertension are less likely to be treated to goal blood pressure because there are conflicting recommendations for what constitutes "optimal" in older adults. The investigators have developed a novel way to non-invasively assess the components of blood vessel stiffness that is related to blood pressure (load-dependent stiffness). This project will generate new knowledge about how different blood pressure treatment goals (intensive vs standard) impact different components of arterial stiffness and if these differences can be explained through genetic analysis. Results from this project will offer the VA an updated blueprint for personalizing blood pressure care in older adults, ultimately improving cardiovascular health.
This description comes directly from the study's public registry record.
Adam Gepner · (608) 256-1901 · adam.gepner@va.gov
Always discuss trial participation with your own doctor first.
| Birmingham VA Medical Center, Birmingham, AL | Birmingham, Alabama, United States | Not Yet Recruiting |
| Tennessee Valley Healthcare System Nashville Campus, Nashville, TN | Nashville, Tennessee, United States | Enrolling By Invitation |
| William S. Middleton Memorial Veterans Hospital, Madison, WI | Madison, Wisconsin, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06495710