Condition: GERD Gastroesophageal Reflux Disease · Laryngopharyngeal Reflux Disease · Sponsor: Insel Gruppe AG, University Hospital Bern
If gastric juice refluxes back into the oesophagus and up into the throat/pharynx/mouth area, causing discomfort or injury, this is known as reflux disease (reflux). Classic symptoms include a burning pain in the middle of the upper abdomen, chest or throat (so-called heartburn), regurgitation of food (acid regurgitation), foreign body sensation in the throat area. There are also changes in the voice, hoarseness, difficulty clearing the throat, difficulty swallowing or a dry, irritating cough due to the chemical irritation of the vocal folds by the gastric juice. There are various causes of reflux. Often there is a weakness of the lower oesophageal sphincter or a hiatal hernia, which favours the reflux of gastric juice. Sometimes there are also movement disorders in the oesophagus or stomach with insufficiently efficient transport of food and liquids. After a consultation with a specialist, three further standard examinations are ordered as a matter of priority for a proper reflux diagnosis: * Gastroscopy: a tube-shaped camera can be used to view the mouth, pharynx, throat, oesophagus, stomach and the beginning of the duodenum and, if necessary, small tissue samples can be taken. * Oesophageal manometry: A pressure measurement of the oesophagus can detect movement disorders or a malfunction of the oesophagus and sphincter. * 24-hour impedance pH measurement: A small tube is placed in the oesophagus through the nose and left there for 24 hours. The probe measures how often g…
This description comes directly from the study's public registry record.
Nina Moser, Dr. med. · +41316323723 · nina.moser@insel.ch
Yves Borbély, Dr. med. · +41316323723 · Yves.Borbely@insel.ch
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| Universitätsspital Inselspital Bern | Bern, Switzerland | Recruiting |
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