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Study identifier: NCT06495190 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Cognition, Flavonoids, Exercise, Gut Microbiome

Condition: Cognitive Decline, Mild  ·  Sponsor: Appalachian State University

PhaseNA
Planned participants240
Who can joinAll sexes, 65 Years to 85 Years
Healthy volunteersYes

About this study

This NIH project will examine the effects of routine flavonoid-rich blueberry intake (12-weeks), combined with or in the absence of regular moderate exercise, on cognitive function in a clinical population of older participants identified as experiencing age-related cognitive changes. This project's hypothesis is that the combination of flavonoid-rich diet and routine physical activity may potentiate cognitive benefits and reduce cognitive decline in an aging population, via mechanisms mediated by the gut microbiome.

This description comes directly from the study's public registry record.

Talk to the study team

David C Nieman, DrPH  ·  8287730056  ·  niemandc@appstate.edu

Camila A Olson, PhD  ·  7042505352  ·  olsonca1@appstate.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Appalachian State University Human Performance Lab, North Carolina Research CampusKannapolis, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06495190