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Study identifier: NCT06493734 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Stereotactic Body Radiation Therapy After Chemotherapy for Unresectable Perihilar Cholangiocarcinoma

Condition: Klatskin Tumor  ·  Sponsor: Erasmus Medical Center

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The objective of this study is to evaluate the efficacy of stereotactic body radiation therapy (SBRT) as additional treatment after standard chemotherapy regarding tumor local control, toxicity, progression-free survival (PFS), overall survival and quality of life. In addition, the objective is to explore the value of immunodynamics in peripheral blood for predicting PFS in patients undergoing chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Alejandra Méndez Romero, MD, PhD  ·  +31 (0)10 7035792  ·  a.mendezromero@erasmusmc.nl

Suus van Loosbroek, MSc  ·  s.vanloosbroek@erasmusmc.nl

Always discuss trial participation with your own doctor first.

Locations (8)

Antwerp University Hospital / Sint-Augustinus GasthuiszustersWilrijk, Antwerp, BelgiumNot Yet Recruiting
University Hospital Brussels / Jules Bordet InstituteBrussels, Brussels Capital, BelgiumNot Yet Recruiting
Radboud University Medical CenterNijmegen, Gelderland, NetherlandsRecruiting
Maastricht University Medical Center+ / Maastro Clinic MaastrichtMaastricht, Limburg, NetherlandsRecruiting
Amsterdam University Medical CenterAmsterdam, North Holland, NetherlandsRecruiting
University Medical Center GroningenGroningen, Provincie Groningen, NetherlandsRecruiting
Erasmus MCRotterdam, South Holland, NetherlandsRecruiting
University Medical Center UtrechtUtrecht, Utrecht, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06493734