Condition: Arthritis, Rheumatoid · Sponsor: Wuerzburg University Hospital
The goal of this clinical trial is to learn if increasing dietary fiber can improve the gut microbiome and reduce disease activity in adults with rheumatoid arthritis (RA). The main questions it aims to answer are: * Can a higher fiber diet improve gut bacteria and produce beneficial short-chain fatty acids (SCFAs)? * Does a higher fiber diet reduce RA symptoms and help with weight loss? Researchers will compare two groups: one group will receive dietary counseling and take 10 grams of psyllium husk daily, while the other group will continue their usual diet. Participants will: * Complete dietary questionnaires at the start, 6 months, and 12 months. * Provide stool samples for gut bacteria and SCFA analysis. * Have their RA activity and body weight monitored regularly. * Receive regular phone calls to support the dietary changes. The study will involve adults with diagnosed RA who can provide informed consent and meet other inclusion criteria.
This description comes directly from the study's public registry record.
Eva C Schwaneck, M.D. · +49 40 1818 81 8343 · e.schwaneck@rheuma-hh.de
Michael Gernert, M.D. · +49 931 201 40 100 · gernert_m1@ukw.de
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| University Würzburg | Würzburg, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06492200