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Study identifier: NCT06491030 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Post-Operative Thoracolumosacral Orthosis for PJK

Condition: Proximal Junctional Kyphosis · Adult Spinal Deformity Surgery · Thoracolumbosacral Orthosis  ·  Sponsor: Hospital for Special Surgery, New York

PhasePhase 4
Planned participants84
Who can joinAll sexes, 30 Years to 75 Years
Healthy volunteersNo

About this study

Proximal junctional kyphosis (PJK) is a common post-operative radiographic finding after surgery for adult spinal deformity (ASD) patients. Although the clinical relevance of isolated PJK is unclear, PJK can progress to symptomatic proximal junctional failures which requires a large revision surgery. Currently, post-operative bracing with a thoracolumbosacral orthosis (TLSO) is common practice after spinal deformity surgery, however the efficacy of this in preventing PJK is unknown. This multi-center randomized control trial identified 84 patients undergoing thoracolumbosacral fusion for ASD and plans to study the efficacy of a novel post-operative TLSO in preventing the development of PJK as defined by the proximal junctional angle on 6-month post-operative X-rays.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (6)

Indiana Spine GroupCarmel, Indiana, United StatesActive Not Recruiting
University of KansasOverland Park, Kansas, United StatesActive Not Recruiting
Hospital for Special SurgeryNew York, New York, United StatesRecruiting
University of Texas Health, HoustonBellaire, Texas, United StatesActive Not Recruiting
Texas Back InstituteDallas, Texas, United StatesActive Not Recruiting
Virgina Mason Franciscan HealthSeattle, Washington, United StatesActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT06491030