Condition: Cervical Cancer · Sponsor: Hannover Medical School
The G-LACC trial is a prospective, interventional, multicenter, open-label, randomized and controlled non-inferiority operative trial. The main goal of this clinical trial is to evaluate the non-inferiority of minimally invasive radical hysterectomy in contrast to abdominal radical hysterectomy in patients with early-stage cervical cancer. In the case of SHAPE criteria, surgery may also be performed as minimally invasive or abdominal simple hysterectomy. The primary criterion for assessment is disease-free survival (DFS). As secondary outcomes, overall survival (OS), disease recurrence, quality of life, intra-/postoperative complications, and serious adverse events are recorded for assessment.
This description comes directly from the study's public registry record.
Peter Hillemanns, Prof. Dr. · +49 (0) 511 532 · frauenklinik@mh-hannover.de
Oliver Papp · +49 (0) 176 1532 · g-lacc.zks@mh-hannover.de
Always discuss trial participation with your own doctor first.
| Ludwigsburg Hospital, Department of Gynecology and Obstetrics | Ludwigsburg, Baden-Wurttemberg, Germany | Recruiting |
| University Medical Center Tübingen, Department of Gynecology | Tübingen, Baden-Wurttemberg, Germany | Recruiting |
| Hochtaunus-Clinics Bad Homburg, Department of Gynecology | Bad Homburg, Hesse, Germany | Recruiting |
| University Medical Center Göttingen, Department of Gynecology and Obstetrics | Göttingen, Lower Saxony, Germany | Recruiting |
| Hannover Medical School, Department of Gynecology and Obstetrics | Hanover, Lower Saxony, Germany | Recruiting |
| Hospital Lüneburg, Department of Gynecology | Lüneburg, Lower Saxony, Germany | Recruiting |
| Hospital Bielefeld - Center, Department of Gynecology | Bielefeld, North Rhine-Westphalia, Germany | Recruiting |
| University Medical Center Düsseldorf, Department of Gynecology and Obstetrics | Düsseldorf, North Rhine-Westphalia, Germany | Recruiting |
| Protestant Hospital Wesel, Gynecological Cancer Center | Wesel, North Rhine-Westphalia, Germany | Recruiting |
| University Medical Center Mainz, Department of Obstetrics and Gynecology | Mainz, Rhineland-Palatinate, Germany | Recruiting |
| University Hospital Schleswig-Holstein, Campus Kiel, Department of Gynecology and Obstetrics | Kiel, Schleswig-Holstein, Germany | Recruiting |
| Vivantes Auguste-Viktoria-Hospital, Department of Gynecology | Berlin Schöneberg, State of Berlin, Germany | Recruiting |
+ 2 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06489795