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Study identifier: NCT06487429 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Short Course Radiotherapy With Sequential Disitamab Vedotin Combined With S-1 and Sintilimab as Whole Course Neoadjuvant Therapy for HER2 Expressed Locally Progressive Gastric Cancer

Condition: Gastric Cancer  ·  Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

PhasePhase 2
Planned participants28
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a prospective, open label, phase II clinical study intended to include patients with locally advanced gastric adenocarcinoma who have not undergone any treatment and are eligible for surgery. The study aims to evaluate the efficacy and safety of the short course sequential radiotherapy regimen of Disitamab Vedotin combined with S-1 and Sintilimab in neoadjuvant therapy for HER2 expressing locally advanced gastric cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Tao Zhang, MD  ·  02785871982  ·  1277577866@qq.com

Zhenyu Lin, MD  ·  15827130393  ·  tojilin@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Zhang TaoWuhan, Hubei, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06487429