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Study identifier: NCT06487377 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

IX001 TCR-T In the Treatment of Advanced Pancreatic Cancer and Colorectal Cancer Induced by KRAS Mutations

Condition: Pancreatic Cancer · Colorectal Cancer  ·  Sponsor: Shanghai Pudong Hospital

PhasePhase 1
Planned participants12
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is a single-arm, single-center, open-label clinical study aimed at evaluating the safety and efficacy of IX001 TCR-T (T cell receptor-engineered T-Cell) injection in patients with advanced pancreatic cancer and colorectal cancer induced by KRAS (Kirsten Rat Sarcoma Viral Oncogene) mutations. A total of 6-18 evaluable patients are planned to be enrolled. The study will include 4 dose groups, using a '3+3' dose escalation design.

This description comes directly from the study's public registry record.

Talk to the study team

MingHua Yu, Dr.  ·  18017821601  ·  minghua_md@fudan.edu.cn

ZhiGuo Long, M.D.  ·  18117253161  ·  zglong1976@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Pudong HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06487377