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Study identifier: NCT06487052 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Evaluation of the Standard Catheter-directed Thrombolysis Effectiveness in Intermediate-High-Risk Pulmonary Embolism Patients

Condition: Pulmonary Embolism Acute  ·  Sponsor: Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A single-center, open-label, randomized comparative study of two treatment strategies in patients with intermediate-high-risk acute pulmonary embolism (PE). Patients will be randomized in a 1:1 ratio to standard anticoagulant therapy or standard catheter-directed thrombolysis (SСDT) with a low dose of alteplase, followed by evaluation of short- and long-term efficacy and safety in each group

This description comes directly from the study's public registry record.

Talk to the study team

Olga Moiseeva  ·  +79213068249  ·  moiseeva_om@almazovcentre.ru

Maria Simakova  ·  +79215898763  ·  simakova_ma@almazovcentre.ru

Always discuss trial participation with your own doctor first.

Locations (1)

Almazov National Medical Research CentreSaint Petersburg, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06487052