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Study identifier: NCT06486454 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Condition: Liver Neoplasms · Primary Liver Cancer · Secondary Liver Cancer  ·  Sponsor: HistoSonics, Inc.

PhaseN/A
Planned participants5000
Who can joinAll sexes, 22 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to collect information on the use of the HistoSonics Edison System for the treatment of liver tumors. The main aim is to understand how different patient characteristics and procedural characteristics may affect histotripsy success at 36 hours post-histotripsy procedure. Sub-studies to the BOOMBOX: Master Study will investigate specific populations and/or clinical questions with more stringent enrollment criteria, standardized testing criteria, and/or follow-up schedule. Any participant enrolled in the BOOMBOX: Master Study that also qualifies for a sub-study may enroll in the sub-study in parallel; sub-studies will be described in separate sub-study protocols. The BOOMBOX: Master Study will collect information about participants before, during, and after the histotripsy treatment procedure. All participants will be followed per standard clinical follow-up based on each site's clinical practice for up to 5 years after the initial histotripsy procedure or until completion of their follow-up in a sub-study, whichever is longer.

This description comes directly from the study's public registry record.

Talk to the study team

Michelle Biedenfeld  ·  605-354-1448  ·  Michelle.Biedenfeld@histosonics.com

Christine Frederiksen  ·  307-262-7118  ·  christine.frederiksen@histosonics.com

Always discuss trial participation with your own doctor first.

Locations (30)

Providence St. JudeFullerton, California, United StatesRecruiting
Mission HospitalMission Viejo, California, United StatesRecruiting
HoagNewport Beach, California, United StatesRecruiting
Sutter Bay HospitalsSan Francisco, California, United StatesRecruiting
Providence Saint John's Health CenterSanta Monica, California, United StatesRecruiting
AdventHealth Altamonte SpringsAltamonte Springs, Florida, United StatesWithdrawn
AdventHealth CelebrationCelebration, Florida, United StatesRecruiting
Lee Health Cancer InstituteFort Myers, Florida, United StatesRecruiting
Baptist Health Miami Cardiac & Vascular InstituteMiami, Florida, United StatesWithdrawn
Northeast Georgia Medical CenterGainesville, Georgia, United StatesRecruiting
RUSH University Medical CenterChicago, Illinois, United StatesRecruiting
University of ChicagoChicago, Illinois, United StatesRecruiting

+ 18 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06486454