Condition: Acute Stress Reaction · Sponsor: University of North Carolina, Chapel Hill
The iCOVER intervention was developed to rapidly restore functioning in individuals experiencing an Acute Stress Reaction (ASR). iCOVER is undergoing widespread adoption but has not been tested for efficacy. iCOVER was designed to be administered by peers, paraprofessionals, or medical personnel in 60-120 seconds, including in military operational environments. The term iCOVER is an acronym that summarizes the six specific steps of the intervention: (1) identify that an individual is experiencing an ASR; (2) Connect with the individual through word, eye contact, and physical touch to draw them back to the present moment; (3) Offer commitment so that the individual feels less psychologically isolated and withdrawn (e.g., "I'm right here with you"); (4) Verify facts - ask simple fact-based questions to engage the individual in deliberate cognitive activity; (5) Establish order of events - briefly review what has happened, what is happening, and what will happen to orient the individual; and (6) Request action to re-engage the individual in purposeful behavior. Participants will be randomly assigned to one of three groups: iCOVER, usual care, or physical presence with reassurance. Investigators have elected to use two different control conditions, in order to examine the reliability of the iCOVER intervention in comparison with two typical responses to individuals experiencing an ASR (i.e., physical presence with reassurance, no specific treatment).
This description comes directly from the study's public registry record.
Jenni Shafer, PhD · 919-360-0681 · jenni_shafer@med.unc.edu
Allison Britt, BS · 919-605-1046 · allison_britt@med.unc.edu
Always discuss trial participation with your own doctor first.
| McLean Hospital, Harvard Medical School | Belmont, Massachusetts, United States | Active Not Recruiting |
| University of Massachusetts Chan Medical School | Worcester, Massachusetts, United States | Recruiting |
| Henry Ford Health System | Detroit, Michigan, United States | Recruiting |
| Washington University, St. Louis | St Louis, Missouri, United States | Recruiting |
| Cooper University Health Care | Camden, New Jersey, United States | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06482567