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Study identifier: NCT06481566 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Almonertinib Combined With Stereotactic Body Radiotherapy (SBRT) in the Treatment of Non-small Cell Lung Cancer With EGFR Sensitive Mutation: a Single-arm, Open-label Clinical Trial

Condition: Non-small Cell Lung Cancer  ·  Sponsor: Chongqing University Cancer Hospital

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if first-line Almonertinib plus upfront stereotactic ablative body radiotherapy (SABR) works to treat EGFR-mutated advanced non-small cell lung cancer. The main questions it aims to answer are: Does first-line Almonertinib plus upfront stereotactic ablative body radiotherapy to residual primary lung lesions prolong the progression-free survival of EGFR-mutated advanced non-small cell lung cancer. Participants will: Take first-line Almonertinib for 2-4 months, then deliver SABR to residual primary lung lesions, after that go on Almonertinib maintenance treatment; Visit the hospital once every 3 months for checkups and tests; Keep a diary of their symptoms ;

This description comes directly from the study's public registry record.

Talk to the study team

Dan Tao, Dr.  ·  +86-15826186392  ·  taodan@cqu.edu.cn

Wei Zhou, Dr.  ·  +86-13883465672  ·  zhouwei998@cqu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Chongqing University Cancer HospitalChongqing, Chongqing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06481566