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Study identifier: NCT06480110 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Ebastine in Combination With Docetaxel as a Treatment for Castration-resistant Metastatic Prostate Cancer

Condition: Metastatic Castration-resistant Prostate Cancer  ·  Sponsor: Rigshospitalet, Denmark

PhasePhase 1/Phase 2
Planned participants30
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label phase I/II study evaluating the addition of ebastine to docetaxel in the treatment for metastatic castration resistant prostate cancer. Patients will be randomized in a 2:1 fashion to receive ebastine daily during and after treatment with a maximum of 10 courses of docetaxel. The primary endpoint is change in the profile of urinary and blood lipids to indicate absorption and possible efficacy of ebastine. Secondary endpoints include PSA response and radiologic progression free survival.

This description comes directly from the study's public registry record.

Talk to the study team

Helle Pappot, DMsc  ·  +4535458403  ·  helle.pappot@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Oncology 5073, RigshospitaletCopenhagen, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT06480110