Condition: Immune Thrombocytopenia With Positive ANA Antibodies · Sponsor: Yunfeng Cheng
The goal of this clinical trial is to learn if hydroxychloroquine (HCQ) plus dexamethasone (DEX) works to treat primary immune thrombocytopenia with positive anti-nuclear antibodies in adults. It will also learn about the safety of HCQ plus DEX. The main questions it aims to answer are: Does HCQ plus DEX raise the response rate in participants, compared to DEX alone? Does HCQ plus DEX prolong the response duration in participants, compared to DEX alone? What medical problems do participants have when taking HCQ plus DEX? Researchers will compare HCQ plus DEX with DEX alone to see if HCQ plus DEX works better to treat primary immune thrombocytopenia with positive anti-nuclear antibodies. Participants will: Take DEX every day for consecutive 4 days ( if platelet count does not recover higher than 30×10\^9/L after 2 weeks, take DEX every day for another consecutive 4 days) with or without HCQ twice a day for 1 year , Visit the clinic once every 1 weeks for the first 4 weeks, and once every 2-4 weeks in the following 11 months for checkups and tests, Keep a diary of their symptoms.
This description comes directly from the study's public registry record.
Lili Ji · 86-021-64041990 · ji.lili@zs-hospital.sh.cn
Always discuss trial participation with your own doctor first.
| Shanghai Zhongshan Hospital | Shanghai, Shanghai Municipality, China | Recruiting |
| Zhongshan Wusong Hospital, Fudan University | Shanghai, Shanghai Municipality, China | Recruiting |
| Shanghai Jinshan Hospital | Shanghai, Shanghai Municipality, China | Recruiting |
| Zhongshan Qingpu Hospital, Fudan University | Shanghai, Shanghai Municipality, China | Recruiting |
| Health and Humanity Research Centre, Hongkong, China. | Hong Kong, Hong Kong | Recruiting |
| Dr. Stanley Ho Medical Foundation | Macao, Macau | Recruiting |
| University Hospital, Macau University of Science and Technology. | Macao, Macau | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06479317