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Study identifier: NCT06479304 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Efficacy and Safety of HCQ Plus Pred in ANA Positive ITP

Condition: Immune Thrombocytopenia With Positive ANA Antibodies  ·  Sponsor: Yunfeng Cheng

PhaseNA
Planned participants129
Who can joinAll sexes, 15 Years to 99 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if hydroxychloroquine (HCQ) plus prednisone (Pred) works to treat primary immune thrombocytopenia with positive anti-nuclear antibodies in adults. It will also learn about the safety of HCQ plus Pred. The main questions it aims to answer are: Does HCQ plus Pred raise the response rate in participants, compared to Pred alone? Does HCQ plus Pred prolong the response duration in participants, compared to Pred alone? What medical problems do participants have when taking HCQ plus Pred? Researchers will compare HCQ plus Pred with Pred alone to see if HCQ plus Pred works better to treat primary immune thrombocytopenia with positive anti-nuclear antibodies. Participants will: Take Pred every day for 6 weeks, with or without HCQ twice a day for 1 year , Visit the clinic once every 1 weeks for the first 4 weeks, and once every 2-4 weeks in the following 11 months for checkups and tests, Keep a diary of their symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Lili Ji  ·  86-021-64041990  ·  ji.lili@zs-hospital.sh.cn

Always discuss trial participation with your own doctor first.

Locations (7)

Shanghai Zhongshan HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Zhongshan Wusong Hospital, Fudan UniversityShanghai, Shanghai Municipality, ChinaRecruiting
Shanghai Jinshan HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Zhongshan Qingpu Hospital, Fudan UniversityShanghai, Shanghai Municipality, ChinaRecruiting
Health and Humanity Research Centre, Hongkong, China.Hong Kong, Hong KongRecruiting
Dr. Stanley Ho Medical FoundationMacao, MacauRecruiting
University Hospital, Macau University of Science and Technology.Macao, MacauRecruiting

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Source record: clinicaltrials.gov/study/NCT06479304