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Study identifier: NCT06478693 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC

Condition: Hepatocellular Carcinoma  ·  Sponsor: Myeloid Therapeutics

PhasePhase 1
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, open-label, Phase 1, first-in-human, dose-escalation study designed to assess the safety, tolerability and define the RP2D of MT-303 alone (Module 1) and in combination with Atezo/Bev (Module 2) in participants with advanced hepatocellular carcinoma expressing GPC3.

This description comes directly from the study's public registry record.

Talk to the study team

Project Manager  ·  +61 2 8569 1400  ·  Lucy.FrereScott@novotech-cro.com

Clinical Department  ·  +1 617 465 1022  ·  303clinical@myeloidtx.com

Always discuss trial participation with your own doctor first.

Locations (9)

St Vincent's HospitalSydney, New South Wales, AustraliaRecruiting
Integrated Clinical Oncology Network (ICON) Pty LtdWoolloongabba, Queensland, AustraliaRecruiting
The Alfred HospitalMelbourne, Victoria, AustraliaRecruiting
Linear Clinical ResearchMurdoch, Western Australia, AustraliaRecruiting
Pusan National Univesity HospitalBusan, South KoreaRecruiting
Cha University Bundang Medical CenterGyeonggi-do, South KoreaRecruiting
Seoul National University HospitalSeoul, South KoreaRecruiting
National Taiwan University HospitalTaipei, TaiwanRecruiting
Taipei Tzu Chi HospitalTaipei, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT06478693