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Study identifier: NCT06478238 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Calcium Folinate Treatment of Spastic Paraplegia 56

Condition: Hereditary Spastic Paraplegia  ·  Sponsor: Shanghai 6th People's Hospital

PhaseEARLY_Phase 1
Planned participants10
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

SPG56 is one of the complicated and early-onset HSP subtypes caused by genetic mutations in CYP2U1. So far, there is no standardized and specific clinical therapy for SPG56. The goal of this clinical trial is to explore the efficacy and safety of calcium folinate in the treatment of SPG56 patients. This study is prospective, open-label and single arm and this trial will last for 6 years. A total of 10 patients will participate and they will receive calcium folinate treatment and professional clinical evaluation regularly.

This description comes directly from the study's public registry record.

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Locations (1)

Shanghai 6th People's HospitaShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06478238