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Study identifier: NCT06477887 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Post Extraction Changes Following Ridge Preservation Using Allogenis Dentin Vs Autogenous Partially Demineralized Dentin

Condition: Socket Preservation  ·  Sponsor: Cairo University

PhaseNA
Planned participants32
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersYes

About this study

Research question: In patients with unrestorable anterior teeth, will the use of allogenic dentin matrix be more effective than autogenous partially demineralized dentine matrix (APDDM) in reducing hard tissue changes after post-extraction ridge preservation in the aesthetic zone? After enrolment, periodontal and radiographic examinations will be conducted, and patients with badly unrestorable teeth in the aesthetic zone will be identified. These patients will undergo measurements of mesio-distal distance between adjacent teeth, corono-apical height of bone, the presence of a labial undercut, dehiscence, or fenestration, and the relationship to adjacent teeth using the transgival probing technique and a preapical radiograph, or CBCT. In both groups, the desired tooth will be atraumatically extracted under local anaesthesia using peritomies and surgical forceps. In the intervention group: preparation of the allogenic dentin matrix. Steps of Allogenic Dentin Processing: Washing with distilled water for 30-120 minutes Ultrasonic cleaning cycles: 1st with distilled water for 5-10 minutes, 2nd with 5-7% hydrogen peroxide 10-30 minutes, then 3 minutes with distilled water for 5-10 minutes at 60-80 Defatting with Chloroform Methanol Solution 1:0.5 for 3-12 hours. Demineralization with 0.5% HCL for 10-60 min Dehydration with Neutral Ethyl Alcohol for 30 minutes, then defatting with Chloroform Methanol Solution 1:0.5 for 3-12 hours Washing with normal saline and freeze-drying, th…

This description comes directly from the study's public registry record.

Talk to the study team

Abdullah Matar  ·  01203333038  ·  dr.@bood@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Cairo UniversityCairo, Cairo, Elmanil, Egypt, 4240101, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT06477887