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Study identifier: NCT06477159 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

Condition: Exocrine Pancreatic Insufficiency  ·  Sponsor: Ohio State University

PhasePhase 4
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study aims to evaluate if a 6-month course of pancrelipase (CREON) treatment improves symptoms of exocrine pancreatic insufficiency (EPI) after an attack of acute pancreatitis. Diagnosis of EPI is measured by a fecal elastase value of \<200, and patients must have a qualifying symptom burden based on the EPI symptom tracker survey. Blood and stool will be analyzed as part of this study, and other surveys of health status will be used to track improvement of symptoms.

This description comes directly from the study's public registry record.

Talk to the study team

Zoe Krebs  ·  614-685-3619  ·  zoe.krebs@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (6)

University of Southern CaliforniaLos Angeles, California, United StatesRecruiting
University of Illinois ChicagoChicago, Illinois, United StatesRecruiting
University of MinnesotaMinneapolis, Minnesota, United StatesNot Yet Recruiting
New York University Langone Medical CenterNew York, New York, United StatesWithdrawn
The Ohio State UniversityColumbus, Ohio, United StatesRecruiting
University of PittsburghPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06477159