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Study identifier: NCT06475807 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dietary Interventions in Cancer Patients Treated With Immune Checkpoint Inhibitors

Condition: Cancer  ·  Sponsor: University of Pittsburgh

PhaseNA
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This pilot trial will study the potential impact of two distinct dietary interventions with sequential use of high-fermented foods and high-fiber supplements on the gut microbiome and antitumor immunity in patients with melanoma and non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors. The trial aims to understand how dietary changes affect the composition and function of the gut microbiome, together with immunological and metabolomic markers in serum in patients with melanoma and NSCLC who are undergoing standard-of-care treatment with a PD-1/PD-L1 Inhibitors (neoadjuvant, adjuvant or consolidation)

This description comes directly from the study's public registry record.

Talk to the study team

Hassane M Zarour, MD  ·  (412) 623-3272  ·  zarourhm@upmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UPMC Hillman Cancer CenterPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06475807