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Study identifier: NCT06475105 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Combination Oral Acetazolamide and Intravenous Furosemide on Acute Decompensated Heart Failure Outcomes

Condition: Acute Decompensated Heart Failure  ·  Sponsor: Universitas Diponegoro

PhasePhase 4
Planned participants66
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Based on ADVOR trial, the potential of adding acetazolamide in increasing the success of decongestion, the amount of natriuresis and diuresis. However, the use of intravenous acetazolamide may not be possible in Indonesia, where the intravenous formulation is not available. This clinical research study is being conducted in single hospitals in Indonesia. We aim to learn if Oral Acetazolamide in addition to Furosemide intravenous works to treat congestion in Acute Decompensated Heart Failure, besides evaluating the total urinary output, change of NT pro BNP level, and safety profile of oral Acetazolamide. The hypothesis of this study is oral acetazolamide works well to achieve successful decongestion.

This description comes directly from the study's public registry record.

Talk to the study team

Inne P Farissa, MD  ·  024-8413476  ·  innefarissa@gmail.com

Tahari B Prakoso, MD  ·  024-8413476  ·  ibas_tbargasp@yahoo.com

Always discuss trial participation with your own doctor first.

Locations (2)

Department of Cardiology and Vascular Medicine, Universitas Diponegoro, Kariadi Central General HospitalSemarang, Central Java, IndonesiaRecruiting
Kariadi Central General HospitalSemarang, Central Java, IndonesiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06475105