Condition: Rejection; Transplant, Kidney · Rejection; Transplant, Pancreas · Sponsor: University of Sydney
After a kidney or a simultaneous kidney-pancreas transplant, some patients may face problems with their new organs. This happens because the body sometimes makes a mistake and tries to get rid of the organ. This problem is called rejection. One type of rejection is known as Acute T cell mediated rejection (TCMR). This can lead to many problems or even stop the transplant from working. Doctors give strong steroids to treat this problem, but there are no rules for how much steroid to give. Too much steroids can cause problems like heart and bone problems, bad infections, and weight gain. That is why we need to find the right dose of steroids for each person to treat this. TACKLE-IT is a study that will try to find the right steroid dose for treating rejection.
This description comes directly from the study's public registry record.
NHMRC Clinical Trials Centre THE UNIVERSITY OF SYDNEY · +61 2 9562 5000 · tackle-it.study@sydney.edu.au
Always discuss trial participation with your own doctor first.
| John Hunter Hospital | Lambton, New South Wales, Australia | Not Yet Recruiting |
| Prince of Wales Hospital | Randwick, New South Wales, Australia | Not Yet Recruiting |
| The Sydney Children's Hospital Network | Westmead, New South Wales, Australia | Not Yet Recruiting |
| Westmead Hospital | Westmead, New South Wales, Australia | Recruiting |
| Queensland Children's Hospital | South Brisbane, Queensland, Australia | Recruiting |
| Princess Alexandra Hospital | Woolloongabba, Queensland, Australia | Not Yet Recruiting |
| Royal Adelaide Hospital | Adelaide, South Australia, Australia | Not Yet Recruiting |
| Monash Medical Centre | Clayton, Victoria, Australia | Not Yet Recruiting |
| Royal Perth Children's hospital | Nedlands, Western Australia, Australia | Not Yet Recruiting |
| Sir Charles Gairdner Hospital | Nedlands, Western Australia, Australia | Not Yet Recruiting |
| Royal Perth Hospital | Perth, Western Australia, Australia | Not Yet Recruiting |
| University of Calgary | Calgary, Alberta, Canada | Not Yet Recruiting |
+ 13 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06474273