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Study identifier: NCT06469515 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Older People's Neurocognitive Recovery After Cardiac Surgery

Condition: Postoperative Cognitive Dysfunction · Postoperative Recovery · Cardiac Surgery  ·  Sponsor: Karolinska Institutet

PhaseN/A
Planned participants220
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

Society is aging and advantages in anesthesia and surgery allow more complex interventions in older persons. Old age is a significant risk factor for the development of postoperative neurocognitive decline characterized by a gradual decrease in performance in several cognitive domains such as memory, attention, information processing, and executive functions, leading to problems with performing daily activities and maintaining independence and postoperative complications. The purpose of this study is to measure older persons' postoperative neurocognitive function, to detect neurocognitive decline, and to identify risk factors and difficulties in daily living as well as explore close relatives' experiences of it. We will include 220 participants ≥65 years of age undergoing planned cardiac surgery. Cognitive symptoms and signs and neurocognitive function will be assessed up to 6 months after surgery. Risk/affected factors such as delirium, functional status, recovery, depression, and healthcare-related quality of life, as well as close relative's experiences and burden, will be measured. The results will have immediate relevance for a substantial number of older persons undergoing surgery, and their close relatives, by enhancing knowledge about postoperative cognitive decline and recovery, and subsequently identifying what support needs to be implemented.

This description comes directly from the study's public registry record.

Talk to the study team

Lina Bergman, PhD  ·  0046 8 524 836 66  ·  lina.bergman@ki.se

Ulrica Nilsson, Professor  ·  ulica.nilsson@ki.se

Always discuss trial participation with your own doctor first.

Locations (1)

Sahlgrenska University HospitalGothenburg, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT06469515