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Study identifier: NCT06466135 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of WAL0921 in Patients With Glomerular Kidney Diseases

Condition: Diabetic Nephropathies · Primary Focal Segmental Glomerulosclerosis · Minimal Change Disease  ·  Sponsor: Walden Biosciences

PhasePhase 2
Planned participants96
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is an adaptive prospective, multi-center, randomized, double-blind, placebo-controlled study to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of WAL0921 in subjects with glomerular kidney disease and proteinuria, including diabetic nephropathy and rare glomerular kidney diseases (primary focal segmental glomerulosclerosis \[FSGS\], treatment-resistant minimal change disease \[TR MCD\], primary immunoglobulin A nephropathy \[IgAN\], and primary membranous nephropathy \[PMN\]). Subjects in this study will be randomized to receive the investigational drug WAL0921 or placebo as an intravenous infusion once every 2 weeks for 7 total infusions. All subjects will be followed for 24 weeks after their last infusion.

This description comes directly from the study's public registry record.

Talk to the study team

Michelle Skupien  ·  8573141961  ·  clinicaltrials@waldenbiosciences.com

Always discuss trial participation with your own doctor first.

Locations (50)

Academic Medical Research InstituteLos Angeles, California, United StatesRecruiting
Colorado Kidney and Vascular CareDenver, Colorado, United StatesRecruiting
D & H Tamarac Research CenterTamarac, Florida, United StatesRecruiting
Fides Clinical ResearchAtlanta, Georgia, United StatesRecruiting
Nephrology Associates of Northern Illinois and Indiana (NANI)Hinsdale, Illinois, United StatesRecruiting
Dunes Clinical ResearchDakota Dunes, South Dakota, United StatesRecruiting
Prolato Clinical Research CenterHouston, Texas, United StatesRecruiting
Clinical Trial NetworkHouston, Texas, United StatesRecruiting
Clinical Advancement CenterSan Antonio, Texas, United StatesRecruiting
Westmead HospitalWestmead, New South Wales, AustraliaRecruiting
Western Health Sunshine HospitalSt Albans, Victoria, AustraliaRecruiting
AIIMS HospitalRaipur, Chhattisgarh, IndiaRecruiting

+ 38 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06466135