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Study identifier: NCT06465550 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase 1 Study of Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major

Condition: β-thalassemia  ·  Sponsor: Shanghai BDgene Co., Ltd.

PhasePhase 1
Planned participants9
Who can joinAll sexes, 3 Years to 35 Years
Healthy volunteersNo

About this study

This study will be intented to evaluate the safety, tolerability, and engraftment efficacy after myeloablative preconditioning and transplantation of autologous CD34+ hematopoietic stem cells transduced with a lentiviral vector encoding the human βA-T87Q-globin gene in patients with transfusion-dependent (TDT) β-thalassemia.

This description comes directly from the study's public registry record.

Talk to the study team

fujun Li  ·  +86-19121311061  ·  fujun.li@bdgene.cn

Always discuss trial participation with your own doctor first.

Locations (3)

Sun Yat-sen Memorial HospitalGuangzhou, Guandong, ChinaRecruiting
The First Affiliated Hospital of Guangxi Medical UniversityNanning, Guangxi, ChinaRecruiting
Shanghai Ruijin Hospital, Shanghai Jiaotong UniversityShanghai, Shanghai City, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06465550