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Study identifier: NCT06465069 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

Condition: Metastatic Solid Tumor · Recurrent Solid Tumor · Advanced Solid Tumor  ·  Sponsor: Eli Lilly and Company

PhasePhase 1
Planned participants420
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to find out whether the study drug, LY4052031, is safe, tolerable and effective in participants with advanced, or metastatic solid tumors including urothelial cancer. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) and phase Ib (dose-expansion). The study will last up to approximately 4 years.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (38)

City of Hope National Medical CenterDuarte, California, United StatesRecruiting
University of California, San Diego (UCSD) - Moores Cancer CenterLa Jolla, California, United StatesNot Yet Recruiting
UCLA Department of Medicine-Hematology/OncologyLos Angeles, California, United StatesRecruiting
Sarah Cannon Research Institute at HealthOneDenver, Colorado, United StatesRecruiting
Florida Cancer Specialists and Research InstituteSt. Petersburg, Florida, United StatesCompleted
University of Chicago HospitalChicago, Illinois, United StatesRecruiting
IU Simon Cancer CenterIndianapolis, Indiana, United StatesNot Yet Recruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
START Midwest Cancer and Hematology Centers of W MichiganGrand Rapids, Michigan, United StatesRecruiting
Washington University School of Medicine in St. LouisSt Louis, Missouri, United StatesRecruiting
NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute)New York, New York, United StatesNot Yet Recruiting
Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting

+ 26 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06465069