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Study identifier: NCT06462365 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

Condition: Hematologic Malignancy · GvHD · GVHD,Acute  ·  Sponsor: Tr1X, Inc.

PhasePhase 1
Planned participants36
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this Phase 1, first in human open-label study is to assess the safety and tolerability of TRX-103 in patients with hematological malignancies undergoing HLA-mismatched related or unrelated hematopoietic stem cell transplantation (HSCT). It is anticipated that up to 36 Subjects will be enrolled during a 18-24 month enrollment period. TRX-103 will be infused one time post HSCT.

This description comes directly from the study's public registry record.

Talk to the study team

Tr1X Clinical Trials  ·  858-283-7879  ·  Tr1xClinicalTrials@Tr1x.bio

Always discuss trial participation with your own doctor first.

Locations (5)

City of HopeDuarte, California, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
University of MinnesotaMinneapolis, Minnesota, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Fred Hutchinson Cancer CenterSeattle, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06462365