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Study identifier: NCT06462248 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Anti-CD19 Chimeric Antigen Receptor Modified T-cell (CAR-T) Therapy for Treatment of B-cell Hematological Malignancies

Condition: Lymphoma, Nonhodgkin · Leukemia, Lymphocytic  ·  Sponsor: Chi Kong Li

PhasePhase 2
Planned participants20
Who can joinAll sexes, 1 Year to no upper limit
Healthy volunteersNo

About this study

CAR-T therapy is now available as a commercial product for treatment of relapsed /refractory acute lymphoblastic leukaemia and B-lymphoma. There is limited access to this new treatment as the product is very expensive. It is imperative to develop cost effective, closed circuit manufacturing systems for CAR-T cells to make CAR-T cells a point-of care production option. Hong Kong Institute of Biotechnology has established a certified GMP facility and utilize the Prodigy system to manufacture CAR-T cells for clinical application. Prince of Wales Hospital and Hong Kong Children's Hospital will conduct the phase II clinical trial to confirm the efficacy and safety of local manufactured CAR-T cell product.

This description comes directly from the study's public registry record.

Talk to the study team

Chi Kong Li, MD  ·  852-35051019  ·  ckli@cuhk.edu.hk

Yvonne Chu, MD  ·  852-35051019  ·  yvonnechu@cuhk.edu.hk

Always discuss trial participation with your own doctor first.

Locations (1)

Prince of Wales HospitalHong Kong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06462248