Condition: Shock · Sponsor: Hospices Civils de Lyon
First described in cardiac surgery, the aortic to radial pressure gradient (ATRAP) is the cause of an underestimation of the aortic pressure with a measure assumed with a radial catheter, and he can concert 1 of 3rd patients. The risks factor well known are small height, previous hypertension, long and difficult surgery, radial artery diameter less than 1.8mm. The ATRAP definition is a pressure difference between radial and femoral (same of the aortic pressure) pressure of 25mmHg on the systolic pressure, or a pressure difference on the mean pressure of 10mmHg, both measures realised by arterial canulation, and with a duration superior than 5 minutes. If this gradient appears in pathophysiological specifics situations, there is a risk of inappropriate administration of vasopressors, with more hospitalisation days, more side effect of vasopressors like an augmentation of myocardial work. The ATRAP is documented in septic shock with a prevalence between 21% and 27%. The ATRAP can appear in shocks, moreover with doses of equivalent norepinephrine of 0.5 µg/kg/min who is use for the definition of refractive shock, the difference between the two pressure is higher if the dose of equivalent norepinephrine is higher than 1µg/kg/min. But the prevalence and risks factors are barely unknowns in this situation. Most of the time, a radial arterial catheter is used for hemodynamic monitoring for his simplicity of utilisation and the lows complications associated. Some medical teams in…
This description comes directly from the study's public registry record.
Matthias Jacquet-lagreze, Dr · 0783426888 · matthias.jacquet-lagreze@chu-lyon.fr
Martin Ruste, Dr · 0472118956 · martin.ruste@chu-lyon.fr
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| Département d'anesthésie Réanimation Hôpital Cardiologique Louis Pradel/Groupement Hospitalier Est | Bron, France | Recruiting |
| Hopital Edouard heriot/Groupement hospitalier Centre, service de médecine intensive réanimation | Lyon, France | Recruiting |
| Hôpital Edouard Heriot/ Groupement hospitalier Centre, service d'anesthésie réanimation | Lyon, France | Recruiting |
| Hôpital de la Croix-Rousse/Groupement hospitalier Nord, service d'anesthésie réanimation | Lyon, France | Recruiting |
| Hôpital Saint Joseph Saint Luc | Lyon, France | Recruiting |
| Centre hospitalier Lyon Sud/Groupement hospitalier Sud, Service d'anesthésie réanimation médecine intensive | Lyon, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06460519