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Study identifier: NCT06458595 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Tolerability of KH658 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

Condition: Age-related Macular Degeneration  ·  Sponsor: Chengdu Origen Biotechnology Co., Ltd.

PhasePhase 1/Phase 2
Planned participants44
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersNo

About this study

KH658 is a adeno-associated virus (AAV) vector-based gene therapy for suprachoroidal space injection. The long-term, stable therapeutic protein after one time injection for nAMD could potentially reduce the treatment burden and maintain vision.

This description comes directly from the study's public registry record.

Talk to the study team

Jiarong Du  ·  +86176 0288 9310  ·  026117@cnkh.com

Always discuss trial participation with your own doctor first.

Locations (1)

Tianjin Medical University General HospitalTianjin, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06458595