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Study identifier: NCT06457425 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase II Clinical Trial of Flonoltinib Maleate Tablet in Intermediate-High Risk Myelofibrosis

Condition: MF,PMF,PPV-MF,PET-MF  ·  Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd

PhasePhase 2
Planned participants75
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This trial adopts a multicenter, open-label, positive drug parallel control clinical trial design, planning to enroll approximately 75 MF participants. Eligible participants will be stratified and assigned in a 1:1:1 ratio to the low-dose flonoltinib maleate tablet group, high-dose flonoltinib maleate tablet group, or the ruxolitinib tablet group. Stratification factor include the Dynamic International Prognostic Scoring System (DIPSS) risk classification (intermediate-2 and high risk)

This description comes directly from the study's public registry record.

Talk to the study team

Liangkun Sun  ·  15885742617  ·  liangkunsun@zenitar.cn

Zheng Jiang  ·  19048075294  ·  zhengjiang@zenitar.cn

Always discuss trial participation with your own doctor first.

Locations (2)

West China Hospital Sichuan UniversityChengdu, Sichuan, ChinaRecruiting
Hematology Hospital, Chinese Academy of Medical SciencesTianjin, Tianjin Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06457425