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Study identifier: NCT06456515 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Regorafenib and Sintilimab in Combination with Electroacupuncture in MSS CRC

Condition: Colorectal Cancer Metastatic  ·  Sponsor: The First People's Hospital of Changzhou

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The aim of this clinical trial is to find out whether Regorafenib and Sintilimab in combination with electroacupuncture works in treating participants with microsatellite stable (MSS) advanced colorectal cancer who have failed one or more second-line standard chemotherapy regimens. It will also learn about the efficacy and safety of the combination therapy. The main questions the trial aims to answer are: Does combination therapy reduce the overall survival time ? What medical problems do people have when they take combination therapy? Participants will Regorafenib, take for 2 weeks and stop for 1 week; Sintilimab, intravenous, every 3 weeks; Electroacupuncture was performed 1 day before, on the day of, and on the 2nd day after each cycle of Sintilimab administration, and patients completed 3 treatments in week 1, followed by 1 treatment per week for 2 weeks, with 5 treatments per dosing

This description comes directly from the study's public registry record.

Talk to the study team

Wenwei Hu  ·  13912330886  ·  ei1979@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The First People's Hospital of ChangzhouChangzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06456515