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Study identifier: NCT06456255 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Bupivacaine and Epinephrine Injection Study

Condition: Sinus Disease · Anesthesia · Bleeding  ·  Sponsor: Amin Javer

PhasePhase 2/Phase 3
Planned participants80
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

Endoscopic sinus surgery (ESS) is a common otolaryngologic procedure that aims to remove the partitions that separate the sinus cavities, remove inflamed tissue, and optimize the sinuses for topical medication use. In this procedure, the surgeon will inject a combination of drugs, local anesthetics, and vasoconstrictors, to reduce bleeding and improve visualization. However, previous studies have shown similar results when injected with only saline. In this study, investigators want to determine if the injection of local anesthesic+vasoconstrictor compared to no injection at all makes any difference in improving the surgeon's visualization during an ESS.

This description comes directly from the study's public registry record.

Talk to the study team

Amin Javer  ·  6048069926  ·  sinusdoc@me.com

Always discuss trial participation with your own doctor first.

Locations (1)

St.Paul's Hospital Sinus CenterVancouver, British Columbia, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06456255