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Study identifier: NCT06455527 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)

Condition: Depression  ·  Sponsor: NYU Langone Health

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This technology development project will be informed and guided by initial data collection of human subject data. For this purpose, the investigators will recruit n=100 people with mild to moderate depression in a double-blinded, parallel-arm, sham-controlled data collection period administered at home and using the investigator's remotely supervised (RS) tDCS protocol. Enrolled participants will complete 10 days of 30-minute tDCS (2.0, DLPFC left anodal) using the RS-tDCS protocol. During each daily session, standard HR and impedance-based HR (i-HR), obtained from the tDCS headset, will be collected to identify a possible marker of response to tDCS in depression. Participants will be randomized 2:1 to active vs. sham tDCS.

This description comes directly from the study's public registry record.

Talk to the study team

Shayna Pehel  ·  929-455-5104  ·  Shayna.Pehel@nyulangone.org

Always discuss trial participation with your own doctor first.

Locations (1)

NYU Langone HealthNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06455527