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Study identifier: NCT06455371 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Patient-centered Dosage of Levothyroxine

Condition: Hypothyroidism · Thyroid Cancer · Thyroid  ·  Sponsor: University Hospital of North Norway

PhaseNA
Planned participants240
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Levothyroxine is the most used thyroid hormone replacement when the thyroid gland is failing. Because dosage adjustment normally takes several months, the investigators have developed a decision support tool (DST) that predicts optimal dosage based on repeated blood samples the first 2 weeks after initiation of therapy. In this randomized study the investigators will include patients that start levothyroxine therapy after total thyroidectomy. The use of DST to advice the physician about an early dosage adjustment will be compared with common clinical practice, that is dosage adjustment every 2 months. The effect of DST use will be assessed by studying the possible relationship between fast optimal dose adjustment, patient reported outcome measures, and ability to work.

This description comes directly from the study's public registry record.

Talk to the study team

Vegard Brun, PhD  ·  0047 77669260  ·  vegard.heimly.brun@unn.no

Solveig Brun, cand.med  ·  004745253006  ·  solveig.konst@unn.no

Always discuss trial participation with your own doctor first.

Locations (3)

Haukeland University HospitalBergen, NorwayRecruiting
Oslo University HospitalOslo, NorwayRecruiting
University Hospital of North NorwayTromsø, NorwayRecruiting

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Source record: clinicaltrials.gov/study/NCT06455371