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Study identifier: NCT06455332 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Predictive Value of the Optic Nerve Involvement in Clinically Isolated Syndrome

Condition: Clinically Isolated Syndrome · Multiple Sclerosis  ·  Sponsor: University Hospital, Lille

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

Optic neuritis (ON) represents around 30% of clinical presentation of clinically isolated syndrome (CIS). Asymptomatic optic nerve involvement is very frequent in all stage of multiple sclerosis (MS) disease including the CIS. However, optic nerve is still not part of MS diagnosis criteria. The main objective of our regional and multicenter study is to evaluate the prognostic value of optic nerve involvement at the earliest clinical stage of MS (=CIS) for the diagnosis of clinically definite MS (2nd clinical relapse) and the delay until the 2nd relapse.

This description comes directly from the study's public registry record.

Talk to the study team

Juliette Bochu  ·  0320444145  ·  juliette.bochu@chu-lille.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital Roger SalengroLille, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06455332