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Study identifier: NCT06453421 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pulmonary Rehabilitation in the Chronically Critically Ill Patient

Condition: Rehabilitation · Chronic Critical Illness  ·  Sponsor: Fondazione Don Carlo Gnocchi ETS

PhaseN/A
Planned participants220
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to learn about the population of chronically critical ill patients who refer to respiratory rehabilitation units. The main questions it aims to answer are: * what are the clinical and pathophysiological characteristics of the population of chronically critical ill patients who refer to respiratory rehabilitation units after hospital admission with the need for prolonged invasive mechanical ventilation via tracheostomy? * what is the response of this patient population to respiratory rehabilitation treatment in terms of functional recovery, weaning from invasive mechanical ventilation, weaning from tracheostomy tube, mortality and return to home? * are there any appreciable indices at admission and/or in the first period of hospitalization which may have a prognostic significance both on short-term objectives (weaning from invasive mechanical ventilation, weaning from the tracheostomy tube) and in the medium-long term (survival, state of health)? Participants will be subjected to a rehabilitation and weaning program consisting of: * physical therapy, * speech therapy, * nutritional assessment and therapy, * in subjects on invasive mechanical ventilation at admission a program of weaning and, if needed, shift from invasive to Non-Invasive Ventilation will be performed.

This description comes directly from the study's public registry record.

Talk to the study team

Francesco Gigliotti, MD  ·  +390557393913  ·  fgigliotti@dongnocchi.it

Elisa Chellini, MD  ·  +390557393914  ·  echellini@dongnocchi.it

Always discuss trial participation with your own doctor first.

Locations (1)

IRCCS Fondazione Don Carlo Gnocchi ONLUSFlorence, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06453421