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Study identifier: NCT06453317 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparison of Ustekinumab, Infliximab and Combination Therapy in Moderately to Severely Active Ulcerative Colitis

Condition: Ulcerative Colitis · Inflammatory Bowel Diseases  ·  Sponsor: Medical University of Lodz

PhasePhase 2
Planned participants172
Who can joinAll sexes, 18 Years to 64 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if combined therapy with infliximab and ustekinumab works better than using these drugs alone in adult patients with ulcerative colitis. It will also learn about the safety of this combination. The main questions it aims to answer are: Does the combination therapy improve the symptoms and heal the intestine quicker and better than these drugs administered alone? Does the combination therapy improve the quality of life better than these drugs administered alone? What medical problems do participants have when taking the combination therapy? Participants: Patients diagnosed with UC will be qualified to biologic therapy (infliximab/ustekinumab/infliximab + ustekinumab). Visit the clinic in stated periods for assessment and to apply medication. Take drugs based on the schedule.

This description comes directly from the study's public registry record.

Talk to the study team

Renata Talar-Wojnarowska, Prof.  ·  +48426776664  ·  renata.talar-wojnarowska@umed.lodz.pl

Adam Fabisiak, PhD, MD  ·  +48500316396  ·  adam.fabisiak@umed.lodz.pl

Always discuss trial participation with your own doctor first.

Locations (1)

Oddział Kliniczny Gastroenterologii Ogólnej i Onkologicznej USK nr 1 im. N. Barlickiego w ŁodziLodz, PolandRecruiting

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Source record: clinicaltrials.gov/study/NCT06453317