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Study identifier: NCT06452732 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AML

Condition: Acute Myeloid Leukemia · Acute Lymphoblastic Leukemia  ·  Sponsor: Peking University People's Hospital

PhaseN/A
Planned participants283
Who can joinAll sexes, N/A to 18 Years
Healthy volunteersNo

About this study

Leukaemia is a major disease that seriously endangers human health, the long-term survival rate of acute myeloid leukaemia receiving conventional chemotherapy is only 10% to 45%, haematological relapse is the main cause of treatment failure in acute myeloid leukaemia, reducing the relapse rate is the key to improving the efficacy of acute leukaemia, biomarker-guided preemptive therapy is an effective way to reduce the recurrence of leukaemia, existing markers to predict the recurrence has a high false Existing markers have high false-negative and false-positive rates for predicting relapse, and improving the accuracy of leukaemia relapse prediction is a major clinical problem that needs to be solved urgently. The group has found that circulating leukaemia stem cells remaining after chemotherapy are the key to relapse, therefore, we propose to conduct a multicentre prospective clinical study on the prediction of acute leukaemia relapse by circulating leukaemia stem cells.

This description comes directly from the study's public registry record.

Talk to the study team

Yingjun Chang Y Prof. Ying-Jun Chang Chang  ·  8610-88325949  ·  rmcyj@bjmu.edu.cn

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Locations (2)

Peking University People's HospitalBeijing, Beijing Municipality, ChinaRecruiting
People's Hospital of Peking UniversityBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06452732