Condition: Breast Cancer · Sponsor: Swiss Cancer Institute
Despite modern surgical and medical treatments, breast cancer can re-occur and lead 20% of patients to death. During the last 20 years, pre-clinical studies have shown that treatment failures may be due to the presence of a sub-type of cancer cells, the cancer stem cells, which are resistant to chemotherapy and radiotherapy. By chance, doxycycline, an old, inexpensive and safe molecule seems to target effectively these cancer stem cells. This study proposes to check for the clinical efficacy of doxycycline to target the cancer stem cells and improve the response to neoadjuvant chemotherapy in ER+/HER2- breast cancers.
This description comes directly from the study's public registry record.
Daniela Zoelly, PhD · +41 31 389 91 91 · trials@swisscancerinstitute.ch
Always discuss trial participation with your own doctor first.
| Kantonsspital St.Gallen | Sankt Gallen, Canton of St. Gallen, Switzerland | Recruiting |
| Clinique de Genolier | Genolier, Canton of Vaud, Switzerland | Recruiting |
| Kantonsspital Winterthur | Winterthur, Canton of Zurich, Switzerland | Recruiting |
| Kantonsspital Graubünden | Chur, Kanton Graubünden, Switzerland | Recruiting |
| Tumor Zentrum Aarau | Aarau, Switzerland | Recruiting |
| Réseau du sein Lausanne | Lausanne, Switzerland | Recruiting |
| Centre Hospitalier Universitaire Vaudois (CHUV) | Lausanne, Switzerland | Recruiting |
| Tumor- und Brustzentrum Ostschweiz | Sankt Gallen, Switzerland | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06452394