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Study identifier: NCT06452316 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency

Condition: Limbal Stem Cell Deficiency  ·  Sponsor: Claris Biotherapeutics, Inc.

PhasePhase 1
Planned participants75
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will enroll subjects with qualifying limbal stem cell deficiency (LSCD). All subjects will receive CSB-001 investigational drug in either one or both study eyes. The study is comprised of two identical phases (Dosing Phase I and II) of test article dosing separated by a 31- to 40-day period, the Dosing Holiday, where no test article is administered. Dosing Phase II is followed by an observational, noninterventional phase (Observation Phase).

This description comes directly from the study's public registry record.

Talk to the study team

Central Operations Representative  ·  919-354-1299  ·  clinicaltrials@clarisbio.com

Always discuss trial participation with your own doctor first.

Locations (6)

Loma Linda University Eye InstituteLoma Linda, California, United StatesRecruiting
Midwest Cornea Associates, LLCCarmel, Indiana, United StatesRecruiting
Francis Price Jr, MDIndianapolis, Indiana, United StatesRecruiting
Minnesota Eye ConsultantsMinnetonka, Minnesota, United StatesRecruiting
Legacy Devers Eye InstitutePortland, Oregon, United StatesRecruiting
Stuart A. Terry, MD PASan Antonio, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06452316